PHARMACEUTICAL INORGANIC CHEMISTRY

PHARMACEUTICAL INORGANIC CHEMISTRY
UNIT I

Impurities in pharmaceutical substances

Sources and types of impurities 
Modified limit test for Chloride and Sulphate 

General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes 

UNIT II

Acids, Bases and Buffers: 

  • Dentifrices
  • Role of fluoride in the treatment of dental caries
  • Desensitizing agents
  • Calcium carbonate
  • Sodium fluoride
  • Zinc eugenol cement
UNIT III 

Gastrointestinal agents 

Acidifiers:

  • Ammonium chloride*
  • Dil. HCl 
  • Ideal properties of antacids
  • combinations of antacids
  • Sodium Bicarbonate*
  • Aluminum hydroxide gel
  • Magnesium hydroxide mixture 

  • Magnesium sulphate 
  • Sodium orthophosphate
  • Kaolin
  • Bentonite 
  • Mechanism, classification 
  • Potassium permanganate 
  • Boric acid
  • Hydrogen peroxide* 
  • Chlorinated lime*
  • Iodine and its preparations 
UNIT IV  

Miscellaneous compounds 

  • Potassium iodide
  • Ammonium chloride*
Emetics: 
  • Copper sulphate*
  • Sodium potassium tartarate 
  • Ferrous sulphate* 
  • Ferrous gluconate 
Poison and Antidote: 
  • Sodium thiosulphate*
  • Activated charcoal 
  • Sodium nitrite333 
  • Zinc Sulphate
  • Potash Alum 
UNIT V 
  • Radio activity
  • Measurement of radioactivity
  • Properties of α, β, γ radiations
  • Half life
  • Radio isotopes and study of radio isotopes - Sodium iodide I131
  • Storage conditions
  • Precautions & pharmaceutical application of radioactive substances.

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