Impurities in pharmaceutical substances:
Sources and types of impurities
Modified limit test
for Chloride and Sulphate
General methods of preparation, assay for the compounds superscripted
with asterisk (*), properties and medicinal uses of inorganic compounds
belonging to the following classes
UNIT II
Acids, Bases and Buffers:
- Functions of major physiological ions,
- Electrolytes used in the replacement therapy:
- Sodium chloride*
- Potassium chloride
- Calcium gluconate*
- Oral Rehydration Salt(ORS)
- Physiological acid base balance
- Dentifrices
- Role of fluoride in the treatment of dental caries
- Desensitizing agents
- Calcium carbonate
- Sodium fluoride
- Zinc eugenol cement
UNIT III
Gastrointestinal agents
Acidifiers:
- Ammonium chloride*
- Dil. HCl
- Ideal properties of antacids
- combinations of antacids
- Sodium Bicarbonate*
- Aluminum hydroxide gel
- Magnesium hydroxide mixture
- Magnesium sulphate
- Sodium orthophosphate
- Kaolin
- Bentonite
- Mechanism, classification
- Potassium permanganate
- Boric acid
- Hydrogen peroxide*
- Chlorinated lime*
- Iodine and its preparations
UNIT IV
Miscellaneous compounds
- Potassium iodide
- Ammonium chloride*
Emetics:
- Copper sulphate*
- Sodium potassium tartarate
- Ferrous sulphate*
- Ferrous gluconate
Poison and Antidote:
- Sodium thiosulphate*
- Activated charcoal
- Sodium nitrite333
- Zinc Sulphate
- Potash Alum
UNIT V
- Radio activity
- Measurement of radioactivity
- Properties of α, β, γ radiations
- Half life
- Radio isotopes and study of radio isotopes - Sodium iodide I131
- Storage conditions
- Precautions & pharmaceutical application of radioactive substances.
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